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Peripheral cannabinoid receptor, CB2, regulates bone mass

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The psychoactive cannabinoids from Cannabis sativa L. and the arachidonic acid-derived endocannabinoids are nonselective natural ligands for cannabinoid receptor type 1 (CB1) and CB2 receptors.

Studies Human Evolution, Paleontology, and Paleoanthropology.These changes are reminiscent of human osteoporosis and may result from differential regulation of trabecular and cortical bone remodeling.Abstract: Although genomic studies suggest that natural selection in humans is ongoing, the strength of selection acting on particular characteristics in human populations has rarely been measured.

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Will Harcourt-Smith, American Museum of Natural History, Vertebrate Paleontology Department, Department Member.The creators recommend keeping a healthy, balanced diet and exercising regularly.

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Here, we used different lines of genetically modified mice to clarify the role played by CB 2 cannabinoid receptors in the regulation of the central immune responses leading to the development of neuropathic pain.

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